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Reliability and correlation of mixture cell correction in methylomic and transcriptomic blood data
OBJECTIVES: The number of DNA methylome and RNA transcriptome studies is growing, but investigators have to consider the cell type composition of tissues used. In blood samples, the data reflect the picture of a mixture of different cells. Specialized algorithms can address the cell-type heterogenei...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017605/ https://www.ncbi.nlm.nih.gov/pubmed/32051015 http://dx.doi.org/10.1186/s13104-020-4936-2 |