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Novel Engraftment and T Cell Differentiation of Human Hematopoietic Cells in ART(−/−) IL2RG(−/Y) SCID Pigs

Pigs with severe combined immunodeficiency (SCID) are an emerging biomedical animal model. Swine are anatomically and physiologically more similar to humans than mice, making them an invaluable tool for preclinical regenerative medicine and cancer research. One essential step in further developing t...

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Detalles Bibliográficos
Autores principales: Boettcher, Adeline N., Li, Yunsheng, Ahrens, Amanda P., Kiupel, Matti, Byrne, Kristen A., Loving, Crystal L., Cino-Ozuna, A. Giselle, Wiarda, Jayne E., Adur, Malavika, Schultz, Blythe, Swanson, Jack J., Snella, Elizabeth M., Ho, Chak-Sum (Sam), Charley, Sara E., Kiefer, Zoe E., Cunnick, Joan E., Putz, Ellie J., Dell'Anna, Giuseppe, Jens, Jackie, Sathe, Swanand, Goldman, Frederick, Westin, Erik R., Dekkers, Jack C. M., Ross, Jason W., Tuggle, Christopher K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017803/
https://www.ncbi.nlm.nih.gov/pubmed/32117254
http://dx.doi.org/10.3389/fimmu.2020.00100