Establishment of recombineering genome editing system in Paraburkholderia megapolitana empowers activation of silent biosynthetic gene clusters

The Burkholderiales are an emerging source of bioactive natural products. Their genomes contain a large number of cryptic biosynthetic gene clusters (BGCs), indicating great potential for novel structures. However, the lack of genetic tools for the most of Burkholderiales strains restricts the minin...

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Detalles Bibliográficos
Autores principales: Zheng, Wentao, Wang, Xue, Zhou, Haibo, Zhang, Youming, Li, Aiying, Bian, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017819/
https://www.ncbi.nlm.nih.gov/pubmed/32053291
http://dx.doi.org/10.1111/1751-7915.13535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017819/
https://www.ncbi.nlm.nih.gov/pubmed/32053291
http://dx.doi.org/10.1111/1751-7915.13535

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