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Establishment of recombineering genome editing system in Paraburkholderia megapolitana empowers activation of silent biosynthetic gene clusters
The Burkholderiales are an emerging source of bioactive natural products. Their genomes contain a large number of cryptic biosynthetic gene clusters (BGCs), indicating great potential for novel structures. However, the lack of genetic tools for the most of Burkholderiales strains restricts the minin...
Autores principales: | Zheng, Wentao, Wang, Xue, Zhou, Haibo, Zhang, Youming, Li, Aiying, Bian, Xiaoying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017819/ https://www.ncbi.nlm.nih.gov/pubmed/32053291 http://dx.doi.org/10.1111/1751-7915.13535 |
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