Alterations in T and B Cell Receptor Repertoires Patterns in Patients With IL10 Signaling Defects and History of Infantile-Onset IBD

Patients with loss-of-function mutations in IL10 or IL10 receptor (IL10R) genes develop severe, medical-refractory, infantile-onset inflammatory bowel disease (IBD). We have previously reported significant alterations in innate and adaptive immune responses in these patients. Next generation sequenc...

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Detalles Bibliográficos
Autores principales: Werner, Lael, Lee, Yu Nee, Rechavi, Erez, Lev, Atar, Yerushalmi, Baruch, Ling, Galina, Shah, Neil, Uhlig, Holm H., Weiss, Batia, Somech, Raz, Snapper, Scott B., Shouval, Dror S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017840/
https://www.ncbi.nlm.nih.gov/pubmed/32117262
http://dx.doi.org/10.3389/fimmu.2020.00109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017840/
https://www.ncbi.nlm.nih.gov/pubmed/32117262
http://dx.doi.org/10.3389/fimmu.2020.00109

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