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Ketoxime peptide ligations: oxidative couplings of alkoxyamines to N-aryl peptides
Chemoselective ligation methods that preserve or introduce side chain diversity are critical for chemical synthesis of peptides and proteins. Starting from ketone substrates instead of aldehydes in oxime ligation reactions would allow substitution at the site of ligation; however, synthetic challeng...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017874/ https://www.ncbi.nlm.nih.gov/pubmed/32110307 http://dx.doi.org/10.1039/c9sc04028e |