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Prostate Cancer Phenotype Influences Bone Mineralization at Metastasis: A Study Using an In Vitro Prostate Cancer Metastasis Testbed

In this study, two types of prostate cancer cell lines, highly metastatic PC‐3 and low metastatic MDA PCa 2b (PCa) were cultured on bone mimetic scaffolds to recapitulate metastasis to bone. A unique in vitro 3D tumor model that uses a sequential culture (SC) of human mesenchymal stem cells followed...

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Detalles Bibliográficos
Autores principales: Molla, MD Shahjahan, Katti, Dinesh R, Iswara, Jairam, Venkatesan, Renugopalkrishnan, Paulmurugan, Ramasamy, Katti, Kalpana S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017885/
https://www.ncbi.nlm.nih.gov/pubmed/32083238
http://dx.doi.org/10.1002/jbm4.10256