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In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan

Unveiling the mechanism of action of a drug is key to understand the benefits and adverse reactions of a medication in an organism. However, in complex diseases such as heart diseases there is not a unique mechanism of action but a wide range of different responses depending on the patient. Explorin...

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Detalles Bibliográficos
Autores principales: Jorba, Guillem, Aguirre-Plans, Joaquim, Junet, Valentin, Segú-Vergés, Cristina, Ruiz, José Luis, Pujol, Albert, Fernández-Fuentes, Narcís, Mas, José Manuel, Oliva, Baldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018085/
https://www.ncbi.nlm.nih.gov/pubmed/32053711
http://dx.doi.org/10.1371/journal.pone.0228926