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In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan
Unveiling the mechanism of action of a drug is key to understand the benefits and adverse reactions of a medication in an organism. However, in complex diseases such as heart diseases there is not a unique mechanism of action but a wide range of different responses depending on the patient. Explorin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018085/ https://www.ncbi.nlm.nih.gov/pubmed/32053711 http://dx.doi.org/10.1371/journal.pone.0228926 |