Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs

Recent human genetic studies suggest that cells of the innate immune system have a primary role in the pathogenesis of neurodegenerative diseases. However, the results from these studies often do not elucidate how the genetic variants affect the biology of these cells to modulate disease risk. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramdhani, Satesh, Navarro, Elisa, Udine, Evan, Efthymiou, Anastasia G., Schilder, Brian M., Parks, Madison, Goate, Alison, Raj, Towfique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018232/
https://www.ncbi.nlm.nih.gov/pubmed/32012164
http://dx.doi.org/10.1371/journal.pgen.1008549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018232/
https://www.ncbi.nlm.nih.gov/pubmed/32012164
http://dx.doi.org/10.1371/journal.pgen.1008549

Ejemplares similares