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Nicotinamide N-methyltransferase expression and its association with phospho-Akt, p53 expression, and survival in high-grade endometrial cancer

BACKGROUND/AIM: Nicotinamide N-methyltransferase (NNMT) is an enzyme that is overexpressed in malignancies. NNMT expression has not been previously studied in endometrial cancer (EC). Increased phospho-Akt (pAkt) levels in response to NNMT overexpression have been reported in in vitro studies of dif...

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Detalles Bibliográficos
Autores principales: AKAR, Serra, HARMANKAYA, İsmail, UĞRAŞ, Serdar, ÇELİK, Çetin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018241/
https://www.ncbi.nlm.nih.gov/pubmed/31652035
http://dx.doi.org/10.3906/sag-1907-166