Structure and activation mechanism of the BBSome membrane protein trafficking complex

Bardet-Biedl syndrome (BBS) is a currently incurable ciliopathy caused by the failure to correctly establish or maintain cilia-dependent signaling pathways. Eight proteins associated with BBS assemble into the BBSome, a key regulator of the ciliary membrane proteome. We report the electron cryomicro...

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Detalles Bibliográficos
Autores principales: Singh, Sandeep K, Gui, Miao, Koh, Fujiet, Yip, Matthew CJ, Brown, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018513/
https://www.ncbi.nlm.nih.gov/pubmed/31939736
http://dx.doi.org/10.7554/eLife.53322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018513/
https://www.ncbi.nlm.nih.gov/pubmed/31939736
http://dx.doi.org/10.7554/eLife.53322

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