Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction

The AAA protein Msp1 extracts mislocalized tail-anchored membrane proteins and targets them for degradation, thus maintaining proper cell organization. How Msp1 selects its substrates and firmly engages them during the energetically unfavorable extraction process remains a mystery. To address this q...

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Detalles Bibliográficos
Autores principales: Wang, Lan, Myasnikov, Alexander, Pan, Xingjie, Walter, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018516/
https://www.ncbi.nlm.nih.gov/pubmed/31999255
http://dx.doi.org/10.7554/eLife.54031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018516/
https://www.ncbi.nlm.nih.gov/pubmed/31999255
http://dx.doi.org/10.7554/eLife.54031

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