Rapid Freezing Enables Aminoglycosides To Eradicate Bacterial Persisters via Enhancing Mechanosensitive Channel MscL-Mediated Antibiotic Uptake

Bacterial persisters exhibit noninherited antibiotic tolerance and are linked to the recalcitrance of bacterial infections. It is very urgent but also challenging to develop antipersister strategies. Here, we report that 10-s freezing with liquid nitrogen dramatically enhances the bactericidal actio...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yanna, Lv, Boyan, Sun, Fengqi, Liu, Jiafeng, Wang, Yan, Gao, Yuanyuan, Qi, Feng, Chang, Zengyi, Fu, Xinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018644/
https://www.ncbi.nlm.nih.gov/pubmed/32047133
http://dx.doi.org/10.1128/mBio.03239-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018644/
https://www.ncbi.nlm.nih.gov/pubmed/32047133
http://dx.doi.org/10.1128/mBio.03239-19

Ejemplares similares