Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative Aspergillus fischeri

Aspergillus fumigatus is a major opportunistic human pathogen. Multiple traits contribute to A. fumigatus pathogenicity, including its ability to produce specific secondary metabolites, such as gliotoxin. Gliotoxin is known to inhibit the host immune response, and genetic mutants that inactivate gli...

Descripción completa

Detalles Bibliográficos
Autores principales: Knowles, Sonja L., Mead, Matthew E., Silva, Lilian Pereira, Raja, Huzefa A., Steenwyk, Jacob L., Goldman, Gustavo H., Oberlies, Nicholas H., Rokas, Antonis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018655/
https://www.ncbi.nlm.nih.gov/pubmed/32047138
http://dx.doi.org/10.1128/mBio.03361-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018655/
https://www.ncbi.nlm.nih.gov/pubmed/32047138
http://dx.doi.org/10.1128/mBio.03361-19

Ejemplares similares