Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescence

Hepatocyte nuclear factor 4α (HNF4α, NR2A1) is a highly conserved member of the nuclear receptor superfamily. Recent advances reveal that it is a key transcriptional regulator of genes, broadly involved in xenobiotic and drug metabolism and also cancers of gastrointestinal tract. However, the exact...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhu, Li, Youjia, Wu, Dinglan, Yu, Shan, Wang, Yuliang, Leung Chan, Franky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018660/
https://www.ncbi.nlm.nih.gov/pubmed/31695151
http://dx.doi.org/10.1038/s41388-019-1080-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018660/
https://www.ncbi.nlm.nih.gov/pubmed/31695151
http://dx.doi.org/10.1038/s41388-019-1080-3

Ejemplares similares