DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals

The DEPTOR-mTORC1/2 axis has been shown to play an important, but a context dependent role in the regulation of proliferation and the survival of various cancer cells in cell culture settings. The in vivo role of DEPTOR in tumorigenesis remains elusive. Here we showed that the levels of both DEPTOR...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoyu, Xiong, Xiufang, Cui, Danrui, Yang, Fei, Wei, Dongping, Li, Haomin, Shu, Jianfeng, Bi, Yanli, Dai, Xiaoqing, Gong, Longyuan, Sun, Yi, Zhao, Yongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018663/
https://www.ncbi.nlm.nih.gov/pubmed/31685947
http://dx.doi.org/10.1038/s41388-019-1085-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018663/
https://www.ncbi.nlm.nih.gov/pubmed/31685947
http://dx.doi.org/10.1038/s41388-019-1085-y

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