CUL4B contributes to cancer stemness by repressing tumor suppressor miR34a in colorectal cancer

Given that colorectal cancer stem cells (CCSCs) play key roles in the tumor dormancy, metastasis, and relapse, targeting CCSCs is a promising strategy in cancer therapy. Here, we aimed to identify the new regulators of CCSCs and found that Cullin 4B (CUL4B), which possesses oncogenic properties in m...

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Detalles Bibliográficos
Autores principales: Li, Yanjun, Hu, Huili, Wang, Yuxing, Fan, Yujia, Yang, Yang, Guo, Beibei, Xie, Xueyong, Lian, Jiabei, Jiang, Baichun, Han, Bo, Wang, Yanlei, Shao, Changshun, Gong, Yaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018700/
https://www.ncbi.nlm.nih.gov/pubmed/32054830
http://dx.doi.org/10.1038/s41389-020-0206-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018700/
https://www.ncbi.nlm.nih.gov/pubmed/32054830
http://dx.doi.org/10.1038/s41389-020-0206-3

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