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Overexpression of Galectin 3 in Pancreatic β Cells Amplifies β-Cell Apoptosis and Islet Inflammation in Type-2 Diabetes in Mice

Aims/Hypothesis: Galectin 3 appears to play a proinflammatory role in several inflammatory and autoimmune diseases. Also, there is evidence that galectin 3 plays a role in both type-1 and type-2 diabetes. During obesity, hematopoietic cell-derived galectin 3 induces insulin resistance. While the rol...

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Detalles Bibliográficos
Autores principales: Petrovic, Ivica, Pejnovic, Nada, Ljujic, Biljana, Pavlovic, Sladjana, Miletic Kovacevic, Marina, Jeftic, Ilija, Djukic, Aleksandar, Draginic, Nevena, Andjic, Marijana, Arsenijevic, Nebojsa, Lukic, Miodrag L., Jovicic, Nemanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018709/
https://www.ncbi.nlm.nih.gov/pubmed/32117058
http://dx.doi.org/10.3389/fendo.2020.00030