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Zebrafish as a Model System for the Study of Severe Ca(V)2.1 (α(1A)) Channelopathies
The P/Q-type Ca(V)2.1 channel regulates neurotransmitter release at neuromuscular junctions (NMJ) and many central synapses. CACNA1A encodes the pore-containing α(1A) subunit of Ca(V)2.1 channels. In humans, de novo CACNA1A mutations result in a wide spectrum of neurological, neuromuscular, and move...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018710/ https://www.ncbi.nlm.nih.gov/pubmed/32116539 http://dx.doi.org/10.3389/fnmol.2019.00329 |