Silencing MYH9 blocks HBx-induced GSK3β ubiquitination and degradation to inhibit tumor stemness in hepatocellular carcinoma

MYH9 has dual functions in tumors. However, its role in inducing tumor stemness in hepatocellular carcinoma (HCC) is not yet determined. Here, we found that MYH9 is an effective promoter of tumor stemness that facilitates hepatocellular carcinoma pathogenesis. Importantly, targeting MYH9 remarkably...

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Detalles Bibliográficos
Autores principales: Lin, Xian, Li, Ai-min, Li, Yong-Hao, Luo, Rong-Cheng, Zou, Yu-Jiao, Liu, Yi-Yi, Liu, Chen, Xie, Ying-Ying, Zuo, Shi, Liu, Zhan, Liu, Zhen, Fang, Wei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018736/
https://www.ncbi.nlm.nih.gov/pubmed/32296025
http://dx.doi.org/10.1038/s41392-020-0111-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018736/
https://www.ncbi.nlm.nih.gov/pubmed/32296025
http://dx.doi.org/10.1038/s41392-020-0111-4

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