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Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma

Despite the introduction of novel targeted therapies, chemotherapy still remains the primary treatment for metastatic melanoma in poorly funded healthcare environments or in case of disease relapse, with no reliable molecular markers for progression-free survival (PFS) available. As chemotherapy pri...

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Detalles Bibliográficos
Autores principales: Guttà, Cristiano, Rahman, Arman, Aura, Claudia, Dynoodt, Peter, Charles, Emilie M., Hirschenhahn, Elodie, Joseph, Jesuchristopher, Wouters, Jasper, de Chaumont, Ciaran, Rafferty, Mairin, Warren, Madhuri, van den Oord, Joost J., Gallagher, William M., Rehm, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018795/
https://www.ncbi.nlm.nih.gov/pubmed/32054850
http://dx.doi.org/10.1038/s41419-020-2309-3