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Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma
Despite the introduction of novel targeted therapies, chemotherapy still remains the primary treatment for metastatic melanoma in poorly funded healthcare environments or in case of disease relapse, with no reliable molecular markers for progression-free survival (PFS) available. As chemotherapy pri...
Autores principales: | Guttà, Cristiano, Rahman, Arman, Aura, Claudia, Dynoodt, Peter, Charles, Emilie M., Hirschenhahn, Elodie, Joseph, Jesuchristopher, Wouters, Jasper, de Chaumont, Ciaran, Rafferty, Mairin, Warren, Madhuri, van den Oord, Joost J., Gallagher, William M., Rehm, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018795/ https://www.ncbi.nlm.nih.gov/pubmed/32054850 http://dx.doi.org/10.1038/s41419-020-2309-3 |
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