Enhanced homologous recombination by the modulation of targeting vector ends

The field of genome editing was founded on the establishment of methods, such as the clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated protein (CRISPR/Cas) system, used to target DNA double-strand breaks (DSBs). However, the efficiency of genome editing also lar...

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Detalles Bibliográficos
Autores principales: Hirotsune, Shinji, Kiyonari, Hiroshi, Jin, Mingyue, Kumamoto, Kanako, Yoshida, Kayo, Shinohara, Miki, Watanabe, Hitomi, Wynshaw-Boris, Anthony, Matsuzaki, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018964/
https://www.ncbi.nlm.nih.gov/pubmed/32054870
http://dx.doi.org/10.1038/s41598-020-58893-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018964/
https://www.ncbi.nlm.nih.gov/pubmed/32054870
http://dx.doi.org/10.1038/s41598-020-58893-9

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