Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity

Trematode infections such as schistosomiasis and fascioliasis cause significant morbidity in an estimated 250 million people worldwide and the associated agricultural losses are estimated at more than US$ 6 billion per year. Current chemotherapy is limited. Triosephosphate isomerase (TIM), an enzyme...

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Detalles Bibliográficos
Autores principales: Ferraro, Florencia, Corvo, Ileana, Bergalli, Lucia, Ilarraz, Andrea, Cabrera, Mauricio, Gil, Jorge, Susuki, Brian M., Caffrey, Conor R., Timson, David J., Robert, Xavier, Guillon, Christophe, Freire, Teresa, Álvarez, Guzmán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018972/
https://www.ncbi.nlm.nih.gov/pubmed/32054976
http://dx.doi.org/10.1038/s41598-020-59460-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018972/
https://www.ncbi.nlm.nih.gov/pubmed/32054976
http://dx.doi.org/10.1038/s41598-020-59460-y

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