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C-phycocyanin attenuates RANKL-induced osteoclastogenesis and bone resorption in vitro through inhibiting ROS levels, NFATc1 and NF-κB activation

Excessive bone loss occurs in inflammatory disorders such as periodontitis and osteoporosis. The underlying mechanism is related to the differentiation of macrophages into multinucleated giant osteoclasts and their bone resorptive activity. C-Phycocyanin (C-PC) is a phycobiliprotein extracted from t...

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Detalles Bibliográficos
Autores principales: AlQranei, Mohammed S., Aljohani, Hanan, Majumdar, Sunipa, Senbanjo, Linda T., Chellaiah, Meenakshi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018981/
https://www.ncbi.nlm.nih.gov/pubmed/32054921
http://dx.doi.org/10.1038/s41598-020-59363-y