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C-phycocyanin attenuates RANKL-induced osteoclastogenesis and bone resorption in vitro through inhibiting ROS levels, NFATc1 and NF-κB activation
Excessive bone loss occurs in inflammatory disorders such as periodontitis and osteoporosis. The underlying mechanism is related to the differentiation of macrophages into multinucleated giant osteoclasts and their bone resorptive activity. C-Phycocyanin (C-PC) is a phycobiliprotein extracted from t...
Autores principales: | AlQranei, Mohammed S., Aljohani, Hanan, Majumdar, Sunipa, Senbanjo, Linda T., Chellaiah, Meenakshi A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018981/ https://www.ncbi.nlm.nih.gov/pubmed/32054921 http://dx.doi.org/10.1038/s41598-020-59363-y |
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