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Integrative data modeling from lung and lymphatic cancer predicts functional roles for miR-34a and miR-16 in cell fate regulation

MiR-34a and miR-16 coordinately control cell cycle checkpoint in non-small cell lung cancer (NSCLC) cells. In cutaneous T-cell lymphoma (CTCL) cells miR-16 regulates a switch between apoptosis and senescence, however the role of miR-34a in this process is unclear. Both miRNAs share many common targe...

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Detalles Bibliográficos
Autores principales: Gupta, Shantanu, Silveira, Daner A., Barbé-Tuana, Florencia M., Mombach, José Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018995/
https://www.ncbi.nlm.nih.gov/pubmed/32054948
http://dx.doi.org/10.1038/s41598-020-59339-y