Development of a Facile Approach for Generating Chemically Modified CRISPR/Cas9 RNA

The RNA-guided, modified type II prokaryotic CRISPR with CRISPR-associated proteins (CRISPR/Cas9) system represents a simple gene-editing platform with applications in biotechnology and also potentially as a therapeutic modality. The system requires a small guide RNA (sgRNA) and a catalytic Cas9 pro...

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Detalles Bibliográficos
Autores principales: Scott, Tristan, Soemardy, Citradewi, Morris, Kevin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019045/
https://www.ncbi.nlm.nih.gov/pubmed/32069700
http://dx.doi.org/10.1016/j.omtn.2020.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019045/
https://www.ncbi.nlm.nih.gov/pubmed/32069700
http://dx.doi.org/10.1016/j.omtn.2020.01.004

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