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Transplantation of hMSCs Genome Edited with LEF1 Improves Cardio-Protective Effects in Myocardial Infarction

Stem cell-based therapy is one of the most attractive approaches to ischemic heart diseases, such as myocardial infarction (MI). We evaluated the cardio-protective effects of the human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) stably expressing lymphoid enhancer-binding factor...

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Detalles Bibliográficos
Autores principales: Cho, Hyun-Min, Lee, Kang-Hoon, Shen, Yi-ming, Shin, Tae-Jin, Ryu, Pan-Dong, Choi, Min-Cheol, Kang, Kyung-Sun, Cho, Je-Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019046/
https://www.ncbi.nlm.nih.gov/pubmed/32069701
http://dx.doi.org/10.1016/j.omtn.2020.01.007