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Development of a high affinity Anticalin(®) directed against human CD98hc for theranostic applications

Enhanced amino acid supply and dysregulated integrin signaling constitute two hallmarks of cancer and are pivotal for metastatic transformation of cells. In line with its function at the crossroads of both processes, overexpression of CD98hc is clinically observed in various cancer malignancies, thu...

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Detalles Bibliográficos
Autores principales: Deuschle, Friedrich-Christian, Morath, Volker, Schiefner, André, Brandt, Corinna, Ballke, Simone, Reder, Sybille, Steiger, Katja, Schwaiger, Markus, Weber, Wolfgang, Skerra, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019167/
https://www.ncbi.nlm.nih.gov/pubmed/32089738
http://dx.doi.org/10.7150/thno.38968