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Development of a high affinity Anticalin(®) directed against human CD98hc for theranostic applications
Enhanced amino acid supply and dysregulated integrin signaling constitute two hallmarks of cancer and are pivotal for metastatic transformation of cells. In line with its function at the crossroads of both processes, overexpression of CD98hc is clinically observed in various cancer malignancies, thu...
Autores principales: | Deuschle, Friedrich-Christian, Morath, Volker, Schiefner, André, Brandt, Corinna, Ballke, Simone, Reder, Sybille, Steiger, Katja, Schwaiger, Markus, Weber, Wolfgang, Skerra, Arne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019167/ https://www.ncbi.nlm.nih.gov/pubmed/32089738 http://dx.doi.org/10.7150/thno.38968 |
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