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Novel Approach for Insertion of Heterologous Sequences into Full-Length ZIKV Genome Results in Superior Level of Gene Expression and Insert Stability

Zika virus (ZIKV) emerged in the Americas in 2015, presenting unique challenges to public health. Unlike other arboviruses of the Flaviviridae family, it is transmissible by sexual contact, which facilitates the spread of the virus into new geographic areas. Additionally, ZIKV can be transmitted fro...

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Detalles Bibliográficos
Autores principales: Volkova, Evgeniya, Tsetsarkin, Konstantin A., Sippert, Emilia, Assis, Felipe, Liu, Guangping, Rios, Maria, Pletnev, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019263/
https://www.ncbi.nlm.nih.gov/pubmed/31947825
http://dx.doi.org/10.3390/v12010061