The R251K Substitution in Viral Protein PB2 Increases Viral Replication and Pathogenicity of Eurasian Avian-like H1N1 Swine Influenza Viruses

The Eurasian avian-like swine (EA) H1N1 virus has affected the Chinese swine industry, and human infection cases have been reported occasionally. However, little is known about the pathogenic mechanism of EA H1N1 virus. In this study, we compared the mouse pathogenicity of A/swine/Guangdong/YJ4/2014...

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Detalles Bibliográficos
Autores principales: Cai, Mengkai, Zhong, Ruting, Qin, Chenxiao, Yu, Zhiqing, Wen, Xiaoyan, Xian, Junsi, Chen, Yongjie, Cai, Yu, Yi, Heyou, Gong, Lang, Zhang, Guihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019279/
https://www.ncbi.nlm.nih.gov/pubmed/31906472
http://dx.doi.org/10.3390/v12010052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019279/
https://www.ncbi.nlm.nih.gov/pubmed/31906472
http://dx.doi.org/10.3390/v12010052

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