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E3 Ligase ITCH Interacts with the Z Matrix Protein of Lassa and Mopeia Viruses and Is Required for the Release of Infectious Particles

Lassa virus (LASV) and Mopeia virus (MOPV) are two closely related, rodent-born mammarenaviruses. LASV is the causative agent of Lassa fever, a deadly hemorrhagic fever endemic in West Africa, whereas MOPV is non-pathogenic in humans. The Z matrix protein of arenaviruses is essential to virus assemb...

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Detalles Bibliográficos
Autores principales: Baillet, Nicolas, Krieger, Sophie, Carnec, Xavier, Mateo, Mathieu, Journeaux, Alexandra, Merabet, Othmann, Caro, Valérie, Tangy, Frédéric, Vidalain, Pierre-Olivier, Baize, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019300/
https://www.ncbi.nlm.nih.gov/pubmed/31906112
http://dx.doi.org/10.3390/v12010049