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Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma
Background: Conclusive evidence on foods, nutrients, or dietary patterns and the risk of renal cell carcinoma (RCC) is lacking in the literature. Methods: We considered data from an Italian hospital-based case–control study (1992–2004) on 767 incident RCC cases and 1534 controls. A posteriori dietar...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019338/ https://www.ncbi.nlm.nih.gov/pubmed/31906594 http://dx.doi.org/10.3390/nu12010134 |
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author | Dalmartello, Michela Bravi, Francesca Serraino, Diego Crispo, Anna Ferraroni, Monica La Vecchia, Carlo Edefonti, Valeria |
author_facet | Dalmartello, Michela Bravi, Francesca Serraino, Diego Crispo, Anna Ferraroni, Monica La Vecchia, Carlo Edefonti, Valeria |
author_sort | Dalmartello, Michela |
collection | PubMed |
description | Background: Conclusive evidence on foods, nutrients, or dietary patterns and the risk of renal cell carcinoma (RCC) is lacking in the literature. Methods: We considered data from an Italian hospital-based case–control study (1992–2004) on 767 incident RCC cases and 1534 controls. A posteriori dietary patterns were identified by applying principal component factor analysis on 28 nutrients derived from a 78-item food-frequency questionnaire. We estimated the odds ratios (ORs) of RCC and corresponding 95% confidence intervals (CIs) for each quartile category (compared to the lowest one) using conditional multiple logistic regression models providing adjustment for major confounding factors. Results: We identified four dietary patterns, named “Animal products”, “Starch-rich”, “Vitamins and fiber”, and “Cooking oils and dressings”. Higher intakes of the “Starch-rich” pattern were positively associated with RCC risk (OR = 1.38, 95% CI: 1.04–1.82 for the highest quartile, p = 0.018). The association was inverse with the “Cooking oils and dressings” pattern (OR = 0.61, 95% CI: 0.47–0.80, p < 0.001), whereas no association was found with “Animal products” and “Vitamins and fiber” patterns. Conclusions: Higher intakes of starch-related foods may increase RCC risk, whereas consumption of olive and seed oils may favorably influence RCC risk. |
format | Online Article Text |
id | pubmed-7019338 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70193382020-03-09 Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma Dalmartello, Michela Bravi, Francesca Serraino, Diego Crispo, Anna Ferraroni, Monica La Vecchia, Carlo Edefonti, Valeria Nutrients Article Background: Conclusive evidence on foods, nutrients, or dietary patterns and the risk of renal cell carcinoma (RCC) is lacking in the literature. Methods: We considered data from an Italian hospital-based case–control study (1992–2004) on 767 incident RCC cases and 1534 controls. A posteriori dietary patterns were identified by applying principal component factor analysis on 28 nutrients derived from a 78-item food-frequency questionnaire. We estimated the odds ratios (ORs) of RCC and corresponding 95% confidence intervals (CIs) for each quartile category (compared to the lowest one) using conditional multiple logistic regression models providing adjustment for major confounding factors. Results: We identified four dietary patterns, named “Animal products”, “Starch-rich”, “Vitamins and fiber”, and “Cooking oils and dressings”. Higher intakes of the “Starch-rich” pattern were positively associated with RCC risk (OR = 1.38, 95% CI: 1.04–1.82 for the highest quartile, p = 0.018). The association was inverse with the “Cooking oils and dressings” pattern (OR = 0.61, 95% CI: 0.47–0.80, p < 0.001), whereas no association was found with “Animal products” and “Vitamins and fiber” patterns. Conclusions: Higher intakes of starch-related foods may increase RCC risk, whereas consumption of olive and seed oils may favorably influence RCC risk. MDPI 2020-01-02 /pmc/articles/PMC7019338/ /pubmed/31906594 http://dx.doi.org/10.3390/nu12010134 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Dalmartello, Michela Bravi, Francesca Serraino, Diego Crispo, Anna Ferraroni, Monica La Vecchia, Carlo Edefonti, Valeria Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma |
title | Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma |
title_full | Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma |
title_fullStr | Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma |
title_full_unstemmed | Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma |
title_short | Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma |
title_sort | dietary patterns in italy and the risk of renal cell carcinoma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019338/ https://www.ncbi.nlm.nih.gov/pubmed/31906594 http://dx.doi.org/10.3390/nu12010134 |
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