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Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma

Background: Conclusive evidence on foods, nutrients, or dietary patterns and the risk of renal cell carcinoma (RCC) is lacking in the literature. Methods: We considered data from an Italian hospital-based case–control study (1992–2004) on 767 incident RCC cases and 1534 controls. A posteriori dietar...

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Autores principales: Dalmartello, Michela, Bravi, Francesca, Serraino, Diego, Crispo, Anna, Ferraroni, Monica, La Vecchia, Carlo, Edefonti, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019338/
https://www.ncbi.nlm.nih.gov/pubmed/31906594
http://dx.doi.org/10.3390/nu12010134
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author Dalmartello, Michela
Bravi, Francesca
Serraino, Diego
Crispo, Anna
Ferraroni, Monica
La Vecchia, Carlo
Edefonti, Valeria
author_facet Dalmartello, Michela
Bravi, Francesca
Serraino, Diego
Crispo, Anna
Ferraroni, Monica
La Vecchia, Carlo
Edefonti, Valeria
author_sort Dalmartello, Michela
collection PubMed
description Background: Conclusive evidence on foods, nutrients, or dietary patterns and the risk of renal cell carcinoma (RCC) is lacking in the literature. Methods: We considered data from an Italian hospital-based case–control study (1992–2004) on 767 incident RCC cases and 1534 controls. A posteriori dietary patterns were identified by applying principal component factor analysis on 28 nutrients derived from a 78-item food-frequency questionnaire. We estimated the odds ratios (ORs) of RCC and corresponding 95% confidence intervals (CIs) for each quartile category (compared to the lowest one) using conditional multiple logistic regression models providing adjustment for major confounding factors. Results: We identified four dietary patterns, named “Animal products”, “Starch-rich”, “Vitamins and fiber”, and “Cooking oils and dressings”. Higher intakes of the “Starch-rich” pattern were positively associated with RCC risk (OR = 1.38, 95% CI: 1.04–1.82 for the highest quartile, p = 0.018). The association was inverse with the “Cooking oils and dressings” pattern (OR = 0.61, 95% CI: 0.47–0.80, p < 0.001), whereas no association was found with “Animal products” and “Vitamins and fiber” patterns. Conclusions: Higher intakes of starch-related foods may increase RCC risk, whereas consumption of olive and seed oils may favorably influence RCC risk.
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spelling pubmed-70193382020-03-09 Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma Dalmartello, Michela Bravi, Francesca Serraino, Diego Crispo, Anna Ferraroni, Monica La Vecchia, Carlo Edefonti, Valeria Nutrients Article Background: Conclusive evidence on foods, nutrients, or dietary patterns and the risk of renal cell carcinoma (RCC) is lacking in the literature. Methods: We considered data from an Italian hospital-based case–control study (1992–2004) on 767 incident RCC cases and 1534 controls. A posteriori dietary patterns were identified by applying principal component factor analysis on 28 nutrients derived from a 78-item food-frequency questionnaire. We estimated the odds ratios (ORs) of RCC and corresponding 95% confidence intervals (CIs) for each quartile category (compared to the lowest one) using conditional multiple logistic regression models providing adjustment for major confounding factors. Results: We identified four dietary patterns, named “Animal products”, “Starch-rich”, “Vitamins and fiber”, and “Cooking oils and dressings”. Higher intakes of the “Starch-rich” pattern were positively associated with RCC risk (OR = 1.38, 95% CI: 1.04–1.82 for the highest quartile, p = 0.018). The association was inverse with the “Cooking oils and dressings” pattern (OR = 0.61, 95% CI: 0.47–0.80, p < 0.001), whereas no association was found with “Animal products” and “Vitamins and fiber” patterns. Conclusions: Higher intakes of starch-related foods may increase RCC risk, whereas consumption of olive and seed oils may favorably influence RCC risk. MDPI 2020-01-02 /pmc/articles/PMC7019338/ /pubmed/31906594 http://dx.doi.org/10.3390/nu12010134 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dalmartello, Michela
Bravi, Francesca
Serraino, Diego
Crispo, Anna
Ferraroni, Monica
La Vecchia, Carlo
Edefonti, Valeria
Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma
title Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma
title_full Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma
title_fullStr Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma
title_full_unstemmed Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma
title_short Dietary Patterns in Italy and the Risk of Renal Cell Carcinoma
title_sort dietary patterns in italy and the risk of renal cell carcinoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019338/
https://www.ncbi.nlm.nih.gov/pubmed/31906594
http://dx.doi.org/10.3390/nu12010134
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