Patient-Derived Colorectal Cancer Organoids Upregulate Revival Stem Cell Marker Genes Following Chemotherapeutic Treatment

Colorectal cancer stem cells have been proposed to drive disease progression, tumour recurrence and chemoresistance. However, studies ablating leucine rich repeat containing G protein-coupled receptor 5 (LGR5)-positive stem cells have shown that they are rapidly replenished in primary tumours. Follo...

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Detalles Bibliográficos
Autores principales: Engel, Rebekah M., Chan, Wing Hei, Nickless, David, Hlavca, Sara, Richards, Elizabeth, Kerr, Genevieve, Oliva, Karen, McMurrick, Paul J., Jardé, Thierry, Abud, Helen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019342/
https://www.ncbi.nlm.nih.gov/pubmed/31906589
http://dx.doi.org/10.3390/jcm9010128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019342/
https://www.ncbi.nlm.nih.gov/pubmed/31906589
http://dx.doi.org/10.3390/jcm9010128

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