Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication

Virus replication displays a large cell-to-cell heterogeneity; yet, not all sources of this variability are known. Here, we study the effect of defective interfering (DI) particle (DIP) co-infection on cell-to-cell variability in influenza A virus (IAV) replication. DIPs contain a large internal del...

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Detalles Bibliográficos
Autores principales: Kupke, Sascha Young, Ly, Lam-Ha, Börno, Stefan Thomas, Ruff, Alexander, Timmermann, Bernd, Vingron, Martin, Haas, Stefan, Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019491/
https://www.ncbi.nlm.nih.gov/pubmed/31936115
http://dx.doi.org/10.3390/v12010071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019491/
https://www.ncbi.nlm.nih.gov/pubmed/31936115
http://dx.doi.org/10.3390/v12010071

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