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Exogenous Gonadotrophin Stimulation Induces Partial Maturation of Human Sertoli Cells in a Testicular Xenotransplantation Model for Fertility Preservation

The future fertility of prepubertal boys with cancer may be irreversibly compromised by chemotherapy and/or radiotherapy. Successful spermatogenesis has not been achieved following the xenotransplantation of prepubertal human testis tissue, which is likely due to the failure of somatic cell maturati...

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Detalles Bibliográficos
Autores principales: Hutka, Marsida, Smith, Lee B., Goossens, Ellen, Wallace, W. Hamish B., Stukenborg, Jan-Bernd, Mitchell, Rod T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019512/
https://www.ncbi.nlm.nih.gov/pubmed/31963729
http://dx.doi.org/10.3390/jcm9010266