Flow-Based Three-Dimensional Co-Culture Model for Long-Term Hepatotoxicity Prediction

We developed concave microwell arrays to establish a size-controllable 3-D co-culture liver model for in vitro drug toxicity testing, to predict hepatotoxicity. The interaction of hepatocytes with hepatic stellate cells (HSCs) was investigated by co-culturing primary 3-D hepatocyte spheroids and HSC...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Yoon Young, Seok, Jin-I, Kim, Dong-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019533/
https://www.ncbi.nlm.nih.gov/pubmed/31892214
http://dx.doi.org/10.3390/mi11010036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019533/
https://www.ncbi.nlm.nih.gov/pubmed/31892214
http://dx.doi.org/10.3390/mi11010036

Ejemplares similares