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Flow-Based Three-Dimensional Co-Culture Model for Long-Term Hepatotoxicity Prediction

We developed concave microwell arrays to establish a size-controllable 3-D co-culture liver model for in vitro drug toxicity testing, to predict hepatotoxicity. The interaction of hepatocytes with hepatic stellate cells (HSCs) was investigated by co-culturing primary 3-D hepatocyte spheroids and HSC...

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Detalles Bibliográficos
Autores principales:	Choi, Yoon Young, Seok, Jin-I, Kim, Dong-Sik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019533/ https://www.ncbi.nlm.nih.gov/pubmed/31892214 http://dx.doi.org/10.3390/mi11010036

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