Cargando…

The Autophagy Protein ATG16L1 Is Required for Sindbis Virus-Induced eIF2α Phosphorylation and Stress Granule Formation

Sindbis virus (SINV) infection induces eIF2α phosphorylation, which leads to stress granule (SG) assembly. SINV infection also stimulates autophagy, which has an important role in controlling the innate immune response. The importance of autophagy to virus-induced translation arrest is not well unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Jefferson, Matthew, Bone, Benjamin, Buck, Jasmine L., Powell, Penny P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019544/
https://www.ncbi.nlm.nih.gov/pubmed/31905741
http://dx.doi.org/10.3390/v12010039