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Proteomic Studies for the Investigation of γ-Globin Induction by Decitabine in Human Primary Erythroid Progenitor Cultures

Reactivation of γ-globin is considered a promising approach for the treatment of β-thalassemia and sickle cell disease. Therapeutic induction of γ-globin expression, however, is fraught with lack of suitable therapeutic targets. The aim of this study was to investigate the effects that treatment wit...

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Detalles Bibliográficos
Autores principales: Theodorou, Andria, Phylactides, Marios, Katsantoni, Eleni, Vougas, Kostas, Garbis, Spyros D., Fanis, Pavlos, Sitarou, Maria, Thein, Swee Lay, Kleanthous, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019605/
https://www.ncbi.nlm.nih.gov/pubmed/31947809
http://dx.doi.org/10.3390/jcm9010134