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Enterovirus 71 VP1 Protein Regulates Viral Replication in SH-SY5Y Cells via the mTOR Autophagy Signaling Pathway

Background: Enterovirus 71 (EV71) is the main pathogen that causes severe hand, foot, and mouth disease with fatal neurological complications. However, its neurovirulence mechanism is still unclear. Candidate virulence sites were screened out at structural protein VP1, but the function of these cand...

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Detalles Bibliográficos
Autores principales: Liu, Zi-Wei, Zhuang, Zhi-Chao, Chen, Rui, Wang, Xiao-Rui, Zhang, Hai-Lu, Li, Shu-Han, Wang, Zhi-Yu, Wen, Hong-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019657/
https://www.ncbi.nlm.nih.gov/pubmed/31861844
http://dx.doi.org/10.3390/v12010011