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Detailed Characteristics of Tonsillar Tumors with Extrachromosomal or Integrated Form of Human Papillomavirus

The human papillomavirus (HPV) integration, the critical step in viral carcinogenesis, most frequently occurs in the E2 gene, which results in its inactivation and in an increase of E6/E7 transcription. However, in a substantial number of tumors, the virus is present in an extrachromosomal form. For...

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Detalles Bibliográficos
Autores principales: Pokrývková, Barbora, Saláková, Martina, Šmahelová, Jana, Vojtěchová, Zuzana, Novosadová, Vendula, Tachezy, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019694/
https://www.ncbi.nlm.nih.gov/pubmed/31905862
http://dx.doi.org/10.3390/v12010042