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TREX1 531C>T Polymorphism is Associated with High Proviral Load Levels in HTLV-1-Infected Persons

Human T-lymphotropic virus type 1 (HTLV-1) deregulates the immune system and cell cycle, resulting in loss of immune tolerance and disease, including HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Three prime repair exonuclease 1 (TREX1) maintains innate immune tolerance of the...

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Detalles Bibliográficos
Autores principales: Silva, Denis de Castro, Amoras, Ednelza da Silva Graça, Moura, Tuane Carolina Ferreira, Lopes, Felipe Teixeira, Gomes, Samara Tatielle Monteiro, da Costa, Carlos A., Sousa, Maísa Silva, Ishak, Ricardo, Vallinoto, Antonio Carlos Rosário, Queiroz, Maria Alice Freitas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019804/
https://www.ncbi.nlm.nih.gov/pubmed/31861565
http://dx.doi.org/10.3390/v12010007