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Highly Sensitive Detection of IDH2 Mutations in Acute Myeloid Leukemia

Background: Acute myeloid leukemia is a heterogeneous hematological disease, characterized by karyotypic and molecular alterations. Mutations in IDH2 have a role in diagnosis and as a minimal residue disease marker. Often the variant allele frequency during follow up is less than 20%, which represen...

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Detalles Bibliográficos
Autores principales: Petiti, Jessica, Rosso, Valentina, Croce, Eleonora, Franceschi, Vanessa, Andreani, Giacomo, Dragani, Matteo, De Gobbi, Marco, Lunghi, Monia, Saglio, Giuseppe, Fava, Carmen, Lo Iacono, Marco, Cilloni, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019902/
https://www.ncbi.nlm.nih.gov/pubmed/31963812
http://dx.doi.org/10.3390/jcm9010271