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A Translational Study of TNF-Alpha Antagonists as an Adjunctive Therapy for Preventing Hemophilic Arthropathy

Repeated intra-articular hemorrhages lead to hemophilic arthropathy in severe hemophilia. Inflammation and pro-inflammatory cytokines (e.g., tumor necrosis factor alpha (TNFα)) might be involved in this pathogenesis. We hypothesized that anti-TNFα may provide adjuvant protection for hemophilic arthr...

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Detalles Bibliográficos
Autores principales: Zhang, Feixu, Xu, Mengyang, Yang, Qin, Hua, Baolai, Xia, Binglan, Lin, Zhenyang, Xiao, Xiao, Monahan, Paul E., Sun, Junjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019955/
https://www.ncbi.nlm.nih.gov/pubmed/31892201
http://dx.doi.org/10.3390/jcm9010075