Low-Dose and Long-Term Olaparib Treatment Sensitizes MDA-MB-231 and SUM1315 Triple-Negative Breast Cancers Spheroids to Fractioned Radiotherapy

The Triple-Negative Breast Cancer subtype (TNBC) is particularly aggressive and heterogeneous. Thus, Poly-ADP-Ribose Polymerase inhibitors were developed to improve the prognosis of patients and treatment protocols are still being evaluated. In this context, we modelized the efficacy of Olaparib (i....

Descripción completa

Detalles Bibliográficos
Autores principales: Dubois, Clémence, Martin, Fanny, Hassel, Chervin, Magnier, Florian, Daumar, Pierre, Aubel, Corinne, Guerder, Sylvie, Mounetou, Emmanuelle, Penault-Lorca, Frédérique, Bamdad, Mahchid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019977/
https://www.ncbi.nlm.nih.gov/pubmed/31888054
http://dx.doi.org/10.3390/jcm9010064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019977/
https://www.ncbi.nlm.nih.gov/pubmed/31888054
http://dx.doi.org/10.3390/jcm9010064

Ejemplares similares