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Addition of a Viral Immunomodulatory Domain to Etanercept Generates a Bifunctional Chemokine and TNF Inhibitor
The inhibition of tumor necrosis factor (TNF) through the use of either antibodies or soluble receptors is a highly effective strategy for the clinical control of chronic inflammatory conditions such as rheumatoid arthritis. Different viruses have similarly exploited this concept by expressing a set...
Autores principales: | Alejo, Alí, Sánchez, Carolina, Amu, Sylvie, Fallon, Padraic G., Alcamí, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020083/ https://www.ncbi.nlm.nih.gov/pubmed/31877657 http://dx.doi.org/10.3390/jcm9010025 |
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