Analysis of Longitudinal‐Ordered Categorical Data for Muscle Spasm Adverse Event of Vismodegib: Comparison Between Different Pharmacometric Models

Longitudinal‐ordered categorical data, common in clinical trials, can be effectively analyzed with nonlinear mixed effect models. In this article, we systematically evaluated the performance of three different models in longitudinal muscle spasm adverse event (AE) data obtained from a clinical trial...

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Detalles Bibliográficos
Autores principales: Lu, Tong, Yang, Yujie, Jin, Jin Y., Kågedal, Matts
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020275/
https://www.ncbi.nlm.nih.gov/pubmed/31877239
http://dx.doi.org/10.1002/psp4.12487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020275/
https://www.ncbi.nlm.nih.gov/pubmed/31877239
http://dx.doi.org/10.1002/psp4.12487

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